Please see this topic:

http://tweaker.userecho.com/topics/651-after-windows-10-creator-update-7tt-says-unable-to-load-library-102/

Please try the "scroll_no_wrap" advanced option in 7+ Taskbar Tweaker beta v5.2.1.4.

Can you please check, do the issues happen if no options are set in the tweaker? If that's the case, can you find out which option causes the issues?

I've replied in the GitHub issue.

A new, compatible version is planned. More information in the blog post:

http://rammichael.com/7-taskbar-tweaker-for-windows-10-creators-update

There's a ticket about it already:

http://tweaker.userecho.com/topics/651-after-windows-10-creator-update-7tt-says-unable-to-load-library-102/

I have never seen such an issue. You're saying: "Same for NEW INSTANCE". Does it mean that there's an issue when 7+ Taskbar Tweaker is not running, too?

Use the disable_topmost advanced option. Refer to the help file for more details.