I believe that it was fixed in v4.5.10!
Thanks everyone for helping me to solve this long-standing bug.
Does the tweaker itself crash, or does explorer crash? Can you provide a crash report?
How do I find event logs when a program crashes?
Hi, same issue here with Win7 Pro 32.
(something like 50% of the time when I wake the computer)

Crash report from windows' crash notification window (Translated from french, field names may not be accurate):

Problem signature:
Problem event name: BEX
Application name: 7+ Taskbar Tweaker.exe
Application version:
Application timestamp: 530913da
Default module name: StackHash_a7aa
Default module version:
Default module timestamp: 00000000
Exception offset: 00000000
Exception code: c0000005
Exception data: 00000008
System version: 6.1.7601.
Regional parameters ID: 1036
Supplementary info #1: a7aa
Supplementary info #2: a7aa91f17ea749d42a4de3b390fa5b3d
Supplementary info #3: a7aa
Supplementary info #4: a7aa91f17ea749d42a4de3b390fa5b3d

Thanks !

Unfortunately, the crash report is not very helpful.
I tried to reproduce it locally, putting the system to sleep multiple times, but the tweaker doesn't crash on my PC.
Do you have a way to reproduce it?
Also, does it crash if you turn off the update checking feature?
Hi RaMMichHael,

I tried but could not find a way to reproduce it consistently. Sometimes it crashes, sometimes not ...
I'll turn off the update checker and let you know in a few days whether it still crashes on wake or not.

Hi again,
Did not have any crash since I turned off the update checker. Good chances it is related, then.

Win 7 Pro (64) SP1
I'm also reporting 7TT crashing when machine awakenes. Also, does not happen after every wakeup. Today, for the first time, I got a "7TT stopped running" Microsoft error popup on the wakeup. Unfortunately, I didn't think about saving a copy, or noting the locations of, the error report files that were sent to Microsoft. It wasn't until later that I thought to check this forum to see whether anyone else was reporting this problem.

I'll keep Update Check enabled and save copies of the error report files sent to Microsoft if that Stopped Running popup occurs again. 
Hi! Thank you very much for this wonderful program, it makes Windows 7 much more pleasant to use.
This bug happens to me often too. 7TT sometimes crashes when resuming from suspend on Windows 7 x64. Explorer does not crash and I can just run 7TT again. Update checking is enabled. I also use Classic Shell, I don't know if it could be related.
Crash report:

Faulting application name: 7+ Taskbar Tweaker.exe, version:, time stamp: 0x530913dd
Faulting module name: ole32.dll, version: 6.1.7601.17514, time stamp: 0x4ce7c92c
Exception code: 0xc0000005
Fault offset: 0x000000000000d89e
Faulting process id: 0xb84
Faulting application start time: 0x01cf4909d1e905c3
Faulting application path: C:\Users\John\AppData\Roaming\7 Taskbar Tweaker\7+ Taskbar Tweaker.exe
Faulting module path: C:\Windows\system32\ole32.dll
Report Id: ffb4667e-b9ce-11e3-9ae8-0019d1fd3b8b
Another one, strangely on another DLL:

Problem signature:
Problem Event Name: APPCRASH
Application Name: 7+ Taskbar Tweaker.exe
Application Version:
Application Timestamp: 530913dd
Fault Module Name: RPCRT4.dll
Fault Module Version: 6.1.7601.18205
Fault Module Timestamp: 51dba4dc
Exception Code: c0020043
Exception Offset: 000000000008a5d3
OS Version: 6.1.7601.
Locale ID: 3082
Additional Information 1: 3e57
Additional Information 2: 3e57682daeac924cabf71877f3387458
Additional Information 3: cb9f
Additional Information 4: cb9f38d4aa47896b743846cdbfbd9d8b
I get a crash all 1-2 days. Sometimes after resuming, sometimes while browsing.

I noticed it the first time after the 4.5 update.

Maybe it's something for this thread:

Problemereignisname: BEX64
Anwendungsname: 7+ Taskbar Tweaker.exe
Anwendungszeitstempel: 536e2ddb
Fehlermodulname: netprofm.dll_unloaded
Fehlermodulzeitstempel: 4a5bdfd0
Ausnahmeoffset: 000007fef8e475f4
Ausnahmecode: c0000005
Ausnahmedaten: 0000000000000008
Betriebsystemversion: 6.1.7601.
Gebietsschema-ID: 1031
Zusatzinformation 1: b4ee
Zusatzinformation 2: b4ee5de6a2322745523997a782b35692
Zusatzinformation 3: 47b2
Zusatzinformation 4: 47b2c14e150201b1d280084a41b9a257
Under review
All I know is that it's caused by the updater mechanism. Unfortunately, the crash report doesn't provide many details, as the code is asynchronous. If you can come up with a way to reproduce the issue, please let me know, I'd really like to fix it.
Same here, Win 7, X64. Will turn off the updater, then.
Thank you for a good and useful program!

Faulting application name: 7+ Taskbar Tweaker.exe, version:, time stamp: 0x52c97941
Faulting module name: ole32.dll, version: 6.1.7601.17514, time stamp: 0x4ce7c92c
Exception code: 0xc0000005
Fault offset: 0x0000000000171ff2
Faulting process id: 0xa1c
Faulting application start time: 0x01cf85935beb0179
Faulting application path: C:\Users\Keo\AppData\Roaming\7 Taskbar Tweaker\7+ Taskbar Tweaker.exe
Faulting module path: C:\Windows\system32\ole32.dll
Report Id: 2182e750-f19a-11e3-a548-00221520d07d
Under review
Here's what I know about the issue:
* It seems to happen only on Windows 7, according to the reports.
* It's related to the networking activity of the update checking. Turning update checking off seems to fix the issue.
* The issue seems to show up when the PC runs for a long time without restarts.

Unfortunately, I wasn't able to find a way to reproduce the crash reliably. Also, stack traces don't provide enough information, as the crash happens in a system module.
Yes, I am also running Windows 7, and I don't usually restart for sometimes more than a month. I use hibernation and not sleeping. I don't have update checking on and I've only had the issue a couple of times since I started using it around the end of August, 2014.
I don't have update checking on
That's unexpected. So you disabled update checking, and you still experience crashes? Could you post a crash report?
Win7 x64 Home Premium
I have update checking on; would a crash dump from WinDbg help? I can grab one the next time it crashes.
It might help. It surely won't hurt, so please grab it.
Also, could you try running the latest beta version and see whether it makes any difference?
It finally (!) crashed ealier today, and I just uploaded the full minidump here:
Running v4.5.8.6 beta.
Thanks, but I'm not able to download the file. What I see is a page which is mostly blank.
Could you upload it to a different place, or email it to me?
Just sent you the Dropbox link.
Win 7 Pro SP1 64-bit all Microsoft updates applied, stand-alone home desktop. Update to my March 15, 2014 initial comment: I didn't note the 7TT version I was running when the "crash on wakeup" problem appeared, but from the Change Log page, apparently it was Ver. 4.4.6 of Feb. 22, 2014 because I've always updated as soon as I saw the notice of a new production version. I've kept Update Checking on and I haven't experienced this "crash on wakeup", or any other crash problem, since Ver 4.5.0 or 4.5.1.

Thank you for your beautiful little program which, for me, discounting this short-term blip, has been very stable.
Just regular anti-bug-report (maybe it will help you somehow):
Windows 7 SP1 x86 (32-bit) + Windows Update turned on (auto-update critical + recommended).
7TT's update checking turned on, each update is installed immediately (or almost) after came.
Using Sleep state regularly and don't restart Windows for a weeks (sometimes don't restart for days/a couple of weeks even after critical windows updates requiring restart).
Don't use Hibernation / Hybrid sleep at all (I can't, there are obstacles).
Have not experienced this "crashes on wakeup" at all. Never saw it.

Thank you for this wonderful superb tool! The most amazing tool for tweaking appearance of Windows 7.
The issue could have been fixed in v4.5.10, but I can't tell for sure, as it's not easy to reproduce.
I believe that it was fixed in v4.5.10!
Thanks everyone for helping me to solve this long-standing bug.